姚伟娟，副教授，博士、硕士研究生导师。

  2002年6月在北京大学医学部获得博士学位，之后赴美国加州大学圣地亚哥分校生物工程系做博士后研究，2008年9月回到北京大学医学部生理与病理生理学系工作。主要从事细胞骨架蛋白在血液细胞流变学、生物力学以及心血管疾病中的作用研究，在JBC、AJP、J Biomechanics、Frontiers in Immunology及Cell Mol Life Sci等杂志上发表SCI论文四十余篇。

代表作：

1. Liu XM, Yu P, Xu YJ, Wang Y, Chen J, Tang FZ, Hu ZQ, Zhou J, Liu LN, Qiu W, Ye YN, Jia Y, Yao WJ*, Long JH*, Zeng Z*. Metformin induces tolerogenicity of dendritic cells by promoting metabolic reprogramming. Cell Mol Life Sci. 80(10):283, 2023.

2. Zhao CR#, Yang QR#, Tang RZ#, Wang L, Wang J, Yang FF, Zhao JN, Zhu JJ, Pang W, Li N, Zhang X, Tian XY, Yao WJ*, Zhou J*. DNA methyltransferase 1 deficiency improves macrophage motility and wound healing by ameliorating cholesterol accumulation. NPJ Regen Med. 8(1):29, 2023.

3. Liu XM#, Xia X#, Xifu Wang, Zhou J, Sung LA, Long JH, Geng XY, Zeng Z*, Yao WJ*. Tropomodulin1 expression increases upon maturation in dendritic cells and promotes their maturation and immune functions. Front Immunol. 11: 587441, 2021.

4. Wang WJ, Xu DW, Zhong LJ, Zhang WX, Kang JH, Zhou J, Ka WB, Sun DG, Xia X, Xie LD*, Yao WJ*. Quantitative proteomics reveals TMOD1-related proteins associated with water balance regulation. PLoS One, 14(7): e0219932, 2019.

5. Xu X, Liu X, Long J, Hu Z, Zheng Q, Zhang C, Li L, Wang Y, Jia Y, Qiu W, Zhou J, Yao WJ*, Zeng Z*. Interleukin-10 reorganizes the cytoskeleton of mature dendritic cells leading to their impaired biophysical properties and motilities. PLoS One, 12(2): e0172523, 2017.

6. Hu ZQ, Xue H, Long JH, Wang Y, Jia Y, Qiu W, Zhou J, Wen ZY, Yao WJ*, Zeng Z*. Biophysical Properties and Motility of Human Mature Dendritic Cells Deteriorated by Vascular Endothelial Growth Factor through Cytoskeleton Remodeling. Int J Mol Sci. 17(11). pii: E1756, 2016.

7. Mu W, Wang X, Zhang X, Zhu S, Sun D, Ka W, Sung LA, Yao WJ*. Fluid shear stress upregulates E-Tmod41 via miR-23b-3p and contributes to F-actin cytoskeleton remodeling during erythropoiesis. PLoS One. 10(8):e0136607, 2015.

8. Du Y, Sun X, Shao Q, Zhang F, Wen Z, Qian Y, Shi B, Yao WJ*, Tian Y*.The biomechanical alterations in the CD14+ monocytes of patients with living donor renal transplantation. Clin Hemorheol Microcirc. 2015;61(1):1-11.

   
   

学术兼职：

中国微循环学会血液流变学委员会委员 (2021-2024)

北京生物医学工程学会生物力学专业委员会委员 (2020-2023)

基金项目:

目前主持1项国家自然科学基金面上项目，2项校企合作的横向项目。

联系方式：

Office: 生理楼

Email: weijuanyao@bjmu.edu.cn

Phone: 010-82802419