康继宏 博士

教授 博士生导师

北京大学基础医学院生理学与病理生理学系

血管稳态与重构全国重点实验室PI

1. 个人简介：

康继宏，中国药科大学药物分析专业学士和硕士，加拿大拉瓦尔大学博士，拉瓦尔大学博士后。目前担任北京大学基础医学院生理学与病理生理学教授，同时任血管稳态与重构全国重点实验室PI，从事生理学教学及科研工作。相关工作以责任（含共同）或第一作者发表在Journal of Cell Biology, PNAS, JCEM, IJMS, BOR, Endocrine Reviews等国际期刊。

2. 研究方向与领域：

1）多囊卵巢综合征的病理机制研究；

2）生殖相关心血管疾病。

3. 研究基金：

国家自然科学基金面上项目  

4. 实验室成员：

吴昊文（2023级硕博连读）

张优优（2024级硕士研究生）

王海龙（2025级博士研究生）

5. 主要代表作：

[1]. Hao Lai#, Xiao Jia#, Qiuxiao Yu, Chenglu Zhang, Jie Qiao, Youfei Guan, and Jihong Kang*. High-Fat Diet Induces Significant Metabolic Disorders in a Mouse Model of Polycystic Ovary Syndrome. Biology of Reproduction, 2014, 91(5):127; 1-11 (recommended by F1000, Rankings: Exceptional)

[2]. Yu Q#, Hao S#, Wang H, Song X, Shen Q, Kang J*. Depression-Like Behavior in a Dehydroepiandrosterone-Induced Mouse Model of Polycystic Ovary Syndrome. Biology of Reproduction, 2016, 95(4): 79; 1-10 (recommended by F1000, Rankings: Very Good)

[3]. Bining Zhao#, Liting Fan#, Mengfei Liu, Haowen Wu, Youyou Zhang, Qiyang Shen and Jihong Kang*. Androgen-Induced Lactic Acid Accumulation Contributes to the Apoptosis of Ovarian Granulosa Cells in Polycystic Ovary Syndrome Mice. Antioxidants (Basel), 2025, 14(10): 1235

[4]. Bining Zhao#, Haowen Wu#, Qiyang Yao, Wenpei Bai*, Jihong Kang*. A ketogenic diet alleviates the apoptosis of granulosa cells by inhibiting the activation of cGAS-STING signaling pathway in PCOS mice. Cell Communication and Signaling, 2024, 22(1): 568

[5]. Qiyang Yao, Xin Zou, Shihe Liu, Haowen Wu, Qiyang Shen and Jihong Kang*. Oxidative Stress as a Contributor to Insulin Resistance in the Skeletal Muscles of Mice with Polycystic Ovary Syndrome. International Journal of Molecular Sciences, 2022, 23(19): 11384

[6]. Haowen Wu, Bining Zhao, Qiyang Yao, Jihong Kang*. Dehydroepiandrosterone-Induced Polycystic Ovary Syndrome Mouse Model Requires Continous Treatments to Maintain Reproductive Phenotypes. Journal of Ovarian Research, 2023, 16(1): 207

[7]. Min Gao#, Rong Cao#, Shengnan Du#, Xiao Jia, Senfeng Zheng, Shizheng Huang, Qifei Han, Jia Liu, Xiaoyan Zhang, Yifei Miao, Jihong Kang*, Jan-Åke Gustafsson*, and Youfei Guan*. Disruption of prostaglandin E2 receptor EP4 impairs urinary concentration via decreasing aquaporin 2 in renal collecting ducts. PNAS, 2015, 112(27): 8397-402 (recommended by F1000, Rankings: Good)

[8]. Jihong Kang and Serge Rivest*. MyD88-deficient bone marrow Cells accelerate onset and reduce survival in a mouse model of amyotrophic lateral sclerosis. Journal of Cell Biology, 2007, 179(6); 1219-30（Highlighted paper）

6. 联系方式 :

招生专业：人体生理学

北京大学基础医学院生理学与病理生理学系

Email: kangjihong@bjmu.edu.cn

电话：010-82805613