Dr Junhua Zhou, PhD, MMed, MBBS

Email： junhua.zhou@bjmu.edu.cn

Phone: +86 (0)10 82805181

Profile

Dr Junhua Zhou is an associate professor of Physiology and Pathophysiology at Peiking University Health Science Center and a member of the Key Laboratory of Molecular Cardiovascular Sciences of Ministry of Education. She completed residency in Internal Medicine at Peking University Health Science Center in 2010. After receiving her PhD degree from the University of Cambridge in 2016, she started her postdoc training at Queen Mary University of London and continued at the University of Cambridge during 2016-2021. Dr. Zhou has published 17 peer-reviewed papers in scientific journals. Her research interest has focused on the physiology and pathophysiology of human adrenals, especially on the mechanism of primary aldosteronism and its precision medicine.

Education

2016 Ph.D. Medicine University of Cambridge

2010 M.Med. Internal Medicine Peking University Health Science Center

2007 M.B.B.S. Clinical Medicine Guangzhou Medical University

Group Members

Bo Liu, Senior Technician

Yanjie Li, PhD Candidate

Shiyu Tong, PhD Candidate

Selected Publications

[1]. Zhou J*, Azizan EA*, Cabrera CP*, Fernandes-Rosa F*, Boulkroun S*, Argentesi G, et al. Somatic mutations of GNA11 and GNAQ in CTNNB1-mutant aldosterone-producing adenomas presenting in puberty, pregnancy or menopause. Nature Genetics. 2021 Sep; 53 (9):1360-1372. (*These authors contributed equally)

[2]. Zhou J*, Lam BY*, Neogi SG, Yeo GS, et al. Transcriptome Pathway Analysis of Pathological and Physiological Aldosterone-Producing Human Tissues. Hypertension. 2016 Dec; 68 (6):1424-1431.

[3]. Zhou J*, Shaikh H L*, Neogi SG, McFarlane I, et al. DACH1, a zona glomerulosa selective gene in the human adrenal, activates transforming growth factor-β signaling and suppresses aldosterone secretion. Hypertension. 2015 May; 65 (5):1103-10.

[4]. Shaikh LH*, Zhou J*, Teo AE, Garg S, et al. LGR5 Activates Noncanonical Wnt Signaling and Inhibits Aldosterone Production in the Human Adrenal. J Clin Endocrinol Metab. 2015 June; 100 (6): E836-44.

[5]. Azizan EA*, Poulsen H*, Tuluc P*, Zhou J*, Clausen MV, et al, Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension, Nature Genetics. 2013 Sep; 45 (9):1055-60.

Contact information

Department of Physiology and Pathophysiology

Peking University Health Science Center

Xueyuan Road 38, Haidian District,

Beijing, China

Email: junhua.zhou@bjmu.edu.cn

Tel：010-82805181