Fu Yi is a Principal Investigator at the Department of Physiology and Pathophysiology of Peking University Health Science Center. His research focuses on exploring the inflammation pathogenesis of major cardiovascular diseases. Dr. Fu’s studies, documented in over 40 articles on journals including Circulation, Cell Research, Circulation Research, Journal of the American Society of Nephrology, received national recognition and is funded by the National Science Fund for Excellent Young Scholars and multiple programs of National Natural Science Foundation of China. He has been awarded the second prize for National Youth Outstanding Physiology Academic Paper by Chinese Association for Physiology. Dr. Fu also serves as committee of Chinese Society of Matrix Biology, Youth committee of Chinese Association for Physiology, as well as the director of Beijing Association for Physiological Sciences.

Selected Publications:

1. Shen Y, Dong Z, Fan F, Li K, Zhu S, Dai R, Huang J, Xie N, He L, Gong Z, Yang X, Tan J, Liu L, Yu F, Tang Y, You Z, Xi J, Wang Y, Kong W*, Zhang Y*, Fu Y（付毅）*. Targeting cytokine-like protein FAM3D lowers blood pressure in hypertension. Cell Rep Med. 2023;4(6):101072.

2. Ma Z, Mao C, Jia Y, Yu F, Xu P, Tan Y, Zou QH, Zhou XJ, Kong W*, Fu Y（付毅）*. ADAMTS7-Mediated Complement Factor H Degradation Potentiates Complement Activation to Contributing to Renal Injuries. J Am Soc Nephrol. 2023;34(2):291-308.

3. Ma Z, Mao C, Chen X, Yang S, Qiu Z, Yu B, Jia Y, Wu C, Wang Y, Wang Y, Gu R, Yu F, Yin Y, Wang X, Xu Q, Liu C, Liao Y*, Zheng J*, Fu Y（付毅）*, Kong W*. Peptide Vaccine Against ADAMTS-7 Ameliorates Atherosclerosis and Postinjury Neointima Hyperplasia. Circulation. 2023;147(9):728-742.

4. Fu Y（付毅）#, Huang Y#, Yang Z#, Chen Y, Zheng J, Mao C, Li Z, Liu Z, Yu B, Li T, Wang M, Xu C, Zhou Y, Zhao G, Jia Y, Guo W, Jia X, Zhang T, Li L, Liu Z, Guo S, Ma M, Zhang H, Liu B, Du J, Wang W, Tang C, Gao P, Xu Q, Wang X, Liu J, Sun J, Kong W. Cartilage oligomeric matrix protein is an endogenous β-arrestin-2-selective allosteric modulator of AT1 receptor counteracting vascular injury. Cell Res. 2021;31(7):773-790.

5. Liu Y, Liu Z, Tang H, Shen Y, Gong Z, Xie N, Zhang X, Wang W, Kong W, Zhou Y*, Fu Y（付毅）*. The N6-methyladenosine (m6A)-forming enzyme METTL3 facilitates M1 macrophage polarization through the methylation of STAT1 mRNA. Am J Physiol Cell Physiol. 2019;317(4):C762-C775.

Fu's Lab

Research Interest：The mechanism of vascular inflammatory diseases