WEIZHEN ZHANG, Professor, AGA fellow, Department of Physiology and Pathophysiology, Peking University Health Science Center.

1. Introduction:

Professor ZHANG received the Ph. D from Peking University Health Science Center in 1994. After finishing his postdoc training at the University of Michigan, Professor ZHANG joined the faculty at the Department of Surgery, University of Michigan and was promoted to Research Assistant, Associate Professor and Professor. In 2007, Dr. ZHANG joined the Department of Physiology and Pathophysiology, Peking University Health Science Center as a Professor. Professor ZHANG has published more than 180 research articles in the prestigious journal such as Nat Commun, Hepatology, PNAS, Diabetes and Diabetologia. His research has been continuously funded by NIH, ADA, National Natural Science Foundation of China, National Program on Key Basic Research Project. Professor ZHANG serves as the editor in chief for Open Journal of Molecular and Integrative Physiology and Open Journal of Gastroenterology, as well as the ad hov. reviewer for prestigious journals including Gut, Int J Obes, Endocrinology, J Endocrinology, AJP.

2. Research of Focus：

Mechanism of energy sensing and regulation of gastrointestinal endocrine hormones on energy metabolism

3. Lab Personnel：

Weizhen Zhang, PI, email: weizhenzhang@bjmu.edu.cn

Lijun Sun, Lab manager, email: lijunsun@bjmu.edu.cn

4、Selected Publications：

1) Luo C, Feng Y, Min J, Zhao Y, Zhu Z, Sun L, Yin H, Yin Y*, Zhang W*. Deficiency of Leucine-Rich Repeat Containing G Protein-Coupled Receptor 4 in Pancreas Reduces β Cell Mass. Adv Sci (Weinh) 2025 12(41):e08858.

2) Gao W, Zhang L, Li Z, Wu T, Lang C, Mulholland MW, Zhang W*. Nuclear acly protects liver from ischemia-reperfusion injury. Hepatology 2024;80(5):1087-1103.

3) Mao Z, Feng M, Li Z, Zhou M, Xu L, Pan K, Wang S, Su W, Zhang W*. ETV5 regulates hepatic fatty acid metabolism through PPAR signaling pathway. Diabetes. 2021 Jan;70(1):214-226.

4) Li Z, Yu R, Yin W, Qin Y, Ma L, Mulholland M, Zhang W*. mTOR Signaling in X/A-Like Cells Contributes to Lipid Homeostasis in Mice. Hepatology. 2019 : 69 (2) :860-875.

5) Mao Z, Lin H, Su W, Li J, Zhou M, Li Z, Zhou B, Yang Q, Zhou M, Pan K, He J, Zhang W*. Deficiency of ZnT8 promotes adiposity and metabolic dysfunction by increasing peripheral serotonin production. Diabetes 2019;68(6):1197-1209.